High fat diets may over-activate destructive heart disease protein: Study
A new research has found that a high-fat diet can cause damage to the muscle cells that make up our hearts by causing a normally harmless protein, Nox2, to become overactive.Consumption of a high-fat diet may be activating a response in the heart that is causing destructive growth and could lead to a greater risk of heart attacks, according to new research.
In a paper published in Biochemical and Biophysical Research Communications, researchers looked at the effect of feeding mice a high fat diet on oxidative stress levels on heart cells. The team from the University of Reading found that cells from the mice had twice the amount of oxidative stress, and led to heart cells being up to 1.8 times bigger due to cardiac hypertrophy which is associated with heart disease.
Named first author Dr Sunbal Naureen Bhatti, from the University of Reading said, “Our research shows one way in which a high-fat diet can cause damage to the muscle cells that make up our hearts.